Bird Flu Outbreak: What You Need to Know

With a second farmer in the United States infected with Avian Influenza A (H5N1), commonly known as bird flu, concerns have started to grow among medical experts. While bird flu infections in humans are rare, these cases show the potential for another virus to spread among humans. However, the Centers for Disease Control and Prevention (CDC) has assured the public that there is currently no evidence of person-to-person bird flu transmission, categorizing the general public’s risk as low.

Where did the new wave of infections start?

H5N1 was first identified in geese in China in 1996, it has since caused outbreaks in various regions, including the U.S. The latest strain, Highly Pathogenic Avian Influenza (HPAI), began spreading in wild birds in Europe in 2020 and reached North America by late 2021. As of May 2024, outbreaks have been reported in poultry across 48 states and in dairy cattle in nine states.

Is there a concern about bird flu infecting cows?

There is a concern about the virus’s potential to mutate and infect dairy cows. However, In an update on May 10, the FDA announced that all 297 samples from their initial retail dairy product survey were negative for H5N1. The relatively mild manifestation of the disease in cows complicates tracking efforts.

Should people worry about bird flu in the food supply?

As noted above, there has been no live bird flu virus found in retail milk and dairy products, mainly due to pasteurization. Still, there are ways people can ensure the food they serve to their families remains safe from viral and bacterial pathogens.

Using a food thermometer is important to verify foods have reached a safe minimum internal temperature:

● Beef, bison, veal, lamb steaks, roasts, chops: 145°F

● Ground meat and sausage: 160°F

● Poultry: 165°F

When handling raw or uncooked meat and poultry, remember to always wash your hands with soap and water and disinfect cooking surfaces.

What are the signs you may have bird flu?

Symptoms can range from mild to severe, including conjunctivitis, cough, fatigue, fever, headaches, muscle aches, runny nose, and shortness of breath. The recent U.S. cases involved mild symptoms and full recoveries.

Are there vaccines or treatments for bird flu?

No bird flu vaccines are currently available, but antiviral drugs like oseltamivir phosphate and baloxavir marboxil are effective treatments if administered promptly. These antivirals can also be used prophylactically following exposure. While not connected to H5N1, the seasonal flu can reduce the risk of getting sick with human influenza viruses and the risk of seasonal and bird flu co-infection.

What should I know if I work around dairy cows?

Individuals with close or prolonged, unprotected exposure to infected birds or animals are at higher risk. If your job involves handling infected or potentially infected birds or other animals, follow these precautions:

● Use protective equipment such as gloves, an N95 respirator, or another well-fitted facemask.

● Wash your hands with soap and water after touching birds.

● Avoid touching your mouth, nose, or eyes after contact with birds or surfaces.

● Change your clothes before contacting healthy domestic poultry and after handling infected or potentially infected birds or animals. Dispose of the gloves and facemask and wash your hands thoroughly with soap and water.

Taking these precautions is crucial, especially if you have a family and young child at home who might have weaker immune systems.

Sources:

CDC: Avian Flu

FDA: Updates on Highly Pathogenic Avian Influenza (HPAI)

National Library of Medicine: The Bird Flu: A New Emerging Pandemic Threat And Its Pharmacological Intervention

Addressing Vaccine Hesitancy and Exploring Advancements in Vaccine Development

There are multiple challenges the world faces when it comes to health. They can range from outbreaks of preventable diseases to a lack of physical activity. But in recent years, vaccine hesitancy has emerged as one of the healthcare system’s biggest challenges. An assessment by the National Library of Medicine found that 6% to 25% of parents may be vaccine-hesitant. Despite the success of vaccines in preventing illness and saving lives, some individuals are still on the fence about vaccines.

Vaccine hesitancy is a complex phenomenon that encompasses a variety of factors. Misinformation and mistrust in the medical establishment play a role along with the rise of social media, allowing for the ability to spread accurate information and falsehoods. Conspiracy theories and misleading narratives can gain traction quickly and create doubt in those who might otherwise choose to vaccinate.

It’s understandable for people to have their concerns but it’s important to remember that vaccines have been instrumental in preventing and controlling infectious diseases, saving millions of lives globally. The technology used to create vaccines has seen significant advancements, allowing for better and safer development.

Traditional vs. Modern Vaccine Technologies:

There are several approaches when it comes to developing a vaccine, including inactivated or attenuated pathogens. While traditional methods remain effective, modern vaccine technologies offer distinct advantages. One of these is recombinant DNA technology, where specific genes from the pathogen are inserted into a harmless virus or bacterium, stimulating an immune response without causing illness. This approach allows for the targeted design of vaccines with improved safety profiles.

Additionally, mRNA vaccines represent a groundbreaking development in vaccine technology. The COVID-19 pandemic highlighted the potential of mRNA vaccines, such as the Pfizer-BioNTech and Moderna vaccines. Unlike traditional vaccines that use weakened or inactivated pathogens, mRNA vaccines teach cells to produce a harmless piece of the virus (spike protein) to trigger an immune response. This allowed for faster vaccine development and production.

Innovative Vaccine Development:

DNA vaccines are rapidly developing and creating a promising future for vaccines. Instead of using proteins or inactivated viruses, DNA vaccines introduce a small piece of DNA into cells that allows it to produce a viral or bacterial protein. This stimulates an immune response, like traditional vaccines.

Another safe and highly effective method of vaccine development is VLP vaccines. This mimics the structure of viruses without containing genetic material. These vaccines help the body build an immune response by presenting it with a virus-like structure, training the immune system to recognize and fight the actual virus. VLP technology has successfully developed vaccines for hepatitis B and human papillomavirus (HPV).

A vaccine that constantly needs to be reformulated each year is the seasonal influenza vaccine. Scientists develop new vaccines each season so that they align with the currently circulating virus strains. Researchers are working on developing universal influenza vaccines to eliminate the need for yearly updates.

Debunking Myths Surrounding Vaccine Safety:

Despite innovative and technological advances in vaccines, there remain many myths and misinformation about vaccines that are helping to fuel hesitancy.

One of the well-known and debunked myths is the link between vaccines and autism. This mainly surrounds the MMR (measles, mumps, and rubella) vaccine, vaccines that contain thimerosal, or too many vaccines. Numerous studies have thoroughly investigated this claim and found no credible evidence supporting a connection between vaccines and the development of autism. The original study suggesting a link has been discredited and retracted, meaning that the paper isn’t part of the scientific record because it was found to be based on scientific misconduct.

Another common misconception is that vaccines contain harmful substances that can cause adverse reactions. Any vaccine can cause side effects, however, most of these symptoms are minor such as a sore arm or low-grade fever. Vaccines undergo meticulous tests for safety, and any ingredients used are thoroughly evaluated. Common vaccine components include weakened or inactivated viruses, proteins, adjuvants (which enhance the body’s immune response), and preservatives. The amounts of these ingredients are well below established safety thresholds, and their inclusion is essential for ensuring vaccine efficacy and stability.

Overall, the way to tackle vaccine hesitancy is through education and research. it is crucial to recognize the impact that vaccines have had on preventing and controlling infectious diseases not only in the United States but around the world. Recognizing myths and misinformation, as well as looking at the proven track record of success and the continued advancements of vaccine technologies, will help build confidence and reduce hesitancy.

Sources

National Library of Medicine: State of Vaccine Hesitancy in the United States

National Library of Medicine: The MMR vaccine and autism: Sensation, refutation, retraction, and fraud

Centers for Disease Control and Prevention: How Vaccines are Developed and Approved for Use

Centers for Disease Control and Prevention: Possible Side Effects from Vaccines

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